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Monday, November 12, 2012

Leukemia is Deadly

It results from the interaction between the segments of chromo more or lesss 9 and 22. In normal individuals, the resultant product of this interaction is a family of enzymes that is supposed to control cell growth. However, in the case of CML sufferers, the supernormal chromosome generates excessive increases in ashen blood cells (2003).

Scientists found that a newly do drugs, ST1571, was effective in curbing the creation of the insane chromosome. Their physical body II study involving over 500 patients who had been hardened unsuccess to the full with interferon alpha a conventional treatment-- showed that 90 part were able to normalize their white blood cell counts later taking the oral drug for only six months. Furthermore, half(a) of the subjects were even able to reduce the "Ph1 positive bone nerve centre cells" by up to 35 share. Based on the findings of this study, scientists were overconfident that ST1571 had the potential of subduing the effects of the disease in the long run, or even on a permanent basis, when administered on its sustain or combined with other drugs ("New Drug Shows outmatch Results," 2003).

Similarly, Christine Gorman's (2001) article titled "Beyond Chemotherapy" discussed the potential of an effective new drug for treating CML. Before delving into the findings about Glivec the experimental drug, Gorman (2003) emphasized the importee of discovering effective drugs by highlighting the inadequacies of the conventional treatments of CML. During these treatments, CML patients


A Lifeline for leukemia: The umbilical cord. (2001, July 9). Business Week, 69.

Scientists who conducted Phase I of the research study found that Glivec was able to bottle up the formation of leukemia cells, thus enabling the regeneration of normal white blood cells. Out of the 53 subjects who were given the highest dose of Glivec, 51 had experienced an improvement in their condition.
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Doctors were unable to find some(prenominal) signs of abnormal chromosomes in seven subjects. Even though some subjects developed bare anemia, the scientists in the study was able to extend this side-effect. Nonetheless, Gorman (2001) also explained that at Phase I of the study, scientists were not fully confident that the leukemia cells might be able to resist the drug in the long run (p. 61).

have to endure severe side-effects of chemotherapy and interferon, which may not even yield positive results. As for patients who have been fortunate enough to find perfect matched donors to go through bone-marrow transplants, they confront a 20 percent jeopardize of dying after undergoing the operation (p. 61).

New drug shows take up results against common type of leukemia. (2003). Bloodline: The Online Resource for Hematology reproduction and News. Retrieved July 21, 2003, from the World Wide Web: http://www.bloodline.net/stories/storyReader$2298

Gorman, C. (2001, April 16). Beyond chemotherapy. Time, 157(15), 61.

In a research study, oncologist Mary J. Laughlin of University Hospitals of Cleveland found that 26 percent of patients suffering from termina
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