Effects of Soy of the Patient in Menopausal Stage and Osteoporosis

Phytooestrogens atomic number 18 reported to bring as weak estrogens. They may also imbibe antiestrogenic effects; it is believed that these effects may be due to estrogen sense organ competition, which may also interfere with hormone replacement therapy. Asian women, naturally consuming large quantities of soybean, have been put in to have fewer hot flashes (Anonymous 163). Goldman states that isoflavones, a class of phytoestrogens, have been found to have the most potent of estrogenic effects. Studies from the 1970s notice the estrogenic effects of isoflavones, and their ability as a relieve oneself of selective estrogen receptor modulator. Phytoestrogens offer relief from flabby menopause symptoms. In a study with 177 women taking 50 mg/day of isoflavones genistein and daidzin (12 weeks), hot flush severity ratings were cut down by 30%, compared to 18% for placebo. Nightsw work throughs were reduced 60%, compared to 30% for placebo (1).

Walling reports that soy contains more than one phytoestrogen, and it is not clear which are having the strongest effect on menopausal symptoms; main subgroups include lignans, isoflavones, and coumestrans. In a study of 104 women with moderate or severe hot flashes daily, dietary soy was given as a add-on for 12 weeks; subjects received 60 g of soy mill or placebo. At the end of this period, serum levels of equol, genistin, and daidzin were higher than service line for the soy group, no changes occurred for

Anonymous. "Phytoestrogens." health check Letter on Drugs and Therapeutics 42.1072 (2000): 18.

Brair, Jordan, Peterson, and Barnes report that the soy isoflavone, genistein, has been found to reduce the activity of osteoclasts or the cells that facilitate bone resorption. An analog to daidzen, a soy isoflavone, is being developed to mimic natural phytochemicals; this confused is called ipraflavone and is being tested for osteoporosis treatment (629-630).

Newman, Laura. "Phyto-oestrogens Get More caution at Menopause Meeting." The Lancet 354.9185 (1999): 1184.

Abelow, Holford, and Insogna report that Asian and vegetarian women question a lower incidence of osteoporosis, than American women, who tend to eat meat and have a lower calcium intake. This may be due to the tendency for replacement of animal protein with soy protein (14).

Kurzer, Mindy S. "Hormonal Effects of Soy Isoflavones: Studies in Premenopausal and postmenopausal Women." The Journal of Nutrition 130.3 (2000): 660S-661S.

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